REAL-WORLD CLINICAL OUTCOMES WITH FIRST-LINE SYSTEMIC TREATMENT AND AVELUMAB MAINTENANCE IN US PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CARCINOMA: THE SPEAR BLADDER-II STUDY

Avelumab first-line maintenance (1LM) is approved for patients with locally advanced or metastatic urothelial carcinoma (la/mUC) who do not have disease progression after platinum-based chemotherapy (PBC).This retrospective study describes real-world treatment patterns and clinical outcomes in patients with la/mUC who initiated first-line (1L) syst

Migrating eastern North American monarch butterflies use a time-compensated sun compass to adjust their flight to the southwest direction.Although the antennal genetic circadian clock and the azimuth of the sun are instrumental for proper function of the compass, it is unclear how these signals are represented on a neuronal level and how they are i

Unilateral absence of pulmonary artery (UAPA) is a rare type of congenital abnormality that may coexist with other congenital abnormalities or present as an isolated lesion, the latter form can Hand Wash be asymptomatic.Surgical procedure is usually carried out when UAPA was diagnosed with significant symptoms, and the aim of surgery is to restore

PurposeThis study investigates how customers perceive corporate social responsibility (CSR) efforts by banks during times of crisis, particularly following the COVID-19 pandemic.It focuses on the authenticity and alignment of CSR actions with customer values and examines how Furniture Cleaner these perceptions influence trust, commitment, and attit